Product Name: 1,2-Bis(Trimethoxysilyl)Ethane
CAS Number: 18406-41-2
Synonyms: BTME, Bis(trimethoxysilyl)ethane
Recommended Use: Used as a silane coupling agent, adhesion promoter, or as a crosslinking agent in polymer and surface modification processes
Manufacturer/Supplier: Contact information for chemical supplier or manufacturer
Emergency Phone Number: Listed for 24-hour hazardous materials emergencies
GHS Classification: Flammable liquids, Category 3; Skin irritation, Category 2; Eye irritation, Category 2A
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. Causes skin irritation. Causes serious eye irritation. Harmful if swallowed.
Pictograms: Flame, Exclamation Mark
Precautionary Statements: Keep away from sparks, heat, and open flames. Wear protective gloves, eye and face protection. Avoid breathing vapors. Wash hands thoroughly after handling. Dispose of contents and container in accordance with local regulations.
Chemical Name: 1,2-Bis(Trimethoxysilyl)Ethane
Chemical Formula: C10H26O6Si2
Concentration: 98% or higher in commercial grades
Impurities: Methanol (potential trace byproduct due to hydrolysis), other silane derivatives as trace contaminants
EC Number: 242-556-5
Inhalation: Move to fresh air and keep at rest. Call a poison center or doctor if you feel unwell. If breathing is difficult, provide oxygen.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water. If irritation develops or persists, consult a physician.
Eye Contact: Rinse cautiously with water for several minutes, removing contact lenses if present. Seek medical attention for persistent redness, pain, or visual disturbance.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Seek immediate medical advice.
Notes for Physician: Treat symptoms. Monitor for signs of respiratory distress or delayed lung effects from vapor inhalation. Provide supportive care as necessary.
Suitable Extinguishing Media: Use alcohol-resistant foam, dry chemical powder, carbon dioxide, or water spray. Do not use a direct jet of water as it may spread the fire.
Hazards from Combustion: Emits toxic fumes of carbon oxides, silicon oxides, and methanol when burned or heated above decomposition temperature.
Protective Equipment for Firefighters: Firefighters should wear self-contained breathing apparatus and full protective gear.
Firefighting Procedures: Move containers from fire area if safe. Cool affected containers with water spray. Prevent runoff from entering drains and waterways.
Explosion Hazard: Vapors can form explosive mixtures with air, especially in confined or poorly-ventilated spaces.
Personal Precautions: Evacuate area of all unnecessary personnel. Avoid breathing vapors. Wear chemical-resistant gloves, protective clothing, and eye/face protection.
Environmental Precautions: Prevent unintended releases from entering soil, sewers, waterways, or drains.
Spill Cleanup Methods: Absorb spill with inert materials such as dry sand or earth. Shovel into suitable container for disposal. Ventilate area.
Decontamination: Wash surface with water and detergent after cleanup is complete. Dispose of contaminated materials according to local regulation.
Emergency Procedures: Inform trained emergency personnel. Isolate spill area. Remove ignition sources.
Handling Guidelines: Work in well-ventilated spaces. Do not eat, drink, or smoke during handling. Remove contaminated clothing and protective equipment before entering eating areas.
Storage Conditions: Store in tightly closed, original containers. Keep away from direct sunlight, heat sources, oxidizers, acids, and moisture. Keep container upright to prevent leaks.
Incompatible Materials: Avoid storing with strong oxidizers, acids, or alkalis.
Technical Measures: Use spark-proof tools and equipment in storage area. Install explosion-proof electrical systems.
Storage Life: Stable under recommended conditions, but hydrolysis will liberate methanol over time in the presence of water or moisture.
Engineering Controls: Use local exhaust ventilation or process enclosures to keep airborne levels below recommended exposure limits.
Occupational Exposure Limit (OEL): No established OEL for BTME, but methanol component (if present) has ACGIH TLV of 200 ppm (TWA).
Personal Protective Equipment (PPE): Chemical-resistant gloves (nitrile), safety goggles, protective clothing, face shield for splashes.
Respiratory Protection: Use a NIOSH/OSHA-approved air-purifying respirator with organic vapor cartridge if exposure limit is likely to be exceeded.
Hygiene Measures: Wash hands after handling, before eating or drinking. Remove contaminated clothing promptly.
Appearance: Colorless to pale yellow clear liquid
Odor: Mild alcohol-like odor
Odor Threshold: Not established
pH: Not applicable
Melting Point/Freezing Point: Below -70°C
Boiling Point: Approximately 290°C
Flash Point: 63°C (closed cup - may vary slightly by supplier)
Evaporation Rate: No data available
Flammability: Flammable liquid
Explosion Limits: Lower: 1.3 vol% (for methanol vapor by hydrolysis); Upper: not determined
Vapor Pressure: 0.09 hPa at 20°C
Vapor Density: >1 (air = 1)
Relative Density: 1.06–1.10 g/mL at 25°C
Solubility in Water: Reacts slowly, forming methanol and silanols
Partition Coefficient (n-octanol/water): Data not available
Autoignition Temperature: 225°C
Decomposition Temperature: No information available
Viscosity: 2–4 mPa.s (25°C)
Chemical Stability: Stable under recommended transport and storage conditions. Hydrolyzes slowly in the presence of moisture, releasing methanol.
Reactivity: Reacts with water, strong acids, and strong bases; produces methanol and silanol by hydrolysis.
Conditions to Avoid: Heat, flame, sparks, and moisture.
Incompatible Materials: Oxidizing agents, acids, bases, water/moisture.
Hazardous Decomposition Products: Methanol, carbon oxides, silicon oxides.
Polymerization: Will not occur under normal handling and storage.
Potential Health Effects: Causes skin and eye irritation. Vapor and mist can cause respiratory tract irritation. Swallowing even small amounts may be harmful, primarily due to possible methanol formation during hydrolysis.
Acute Toxicity: Oral LD50 (Rat): >2000 mg/kg. Dermal LD50 (Rabbit): >2000 mg/kg. Inhalation LC50 not established for BTME.
Chronic Effects: Repeated or prolonged skin contact may cause dermatitis. No long-term carcinogenicity or reproductive toxicity studies available.
Route of Exposure: Inhalation, skin, eyes, ingestion.
Symptoms: Redness, burning, irritation, headache, dizziness, slurred speech, nausea with excessive exposure.
Target Organs: Eyes, skin, central nervous system (if methanol is formed and absorbed).
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, or OSHA.
Ecotoxicity: Data limited, but hydrolysis product methanol is acutely toxic to aquatic organisms.
Persistence and Degradability: Hydrolyzes in water, producing methanol and silanol derivatives, which degrade to inorganic silicates over time.
Bioaccumulative Potential: Low for BTME itself; methanol has low bioconcentration in aquatic organisms.
Mobility in Soil: Silanes hydrolyze and bind to soil; methanol is mobile and water-soluble.
Other Adverse Effects: Avoid uncontrolled release to the environment. Chemical supports combustion on water surfaces if spilled in large quantities.
Waste Disposal Methods: Dispose of as hazardous waste through a licensed disposal contractor. Incineration recommended if permitted by local regulations.
Contaminated Packaging: Empty containers retain residue. Dispose as hazardous waste.
Special Precautions: Neutralize or absorb spillage with appropriate materials before landfilling, only if accepted by local rules. Do not allow to enter drains or water courses.
Waste Code: Follow local, state, and federal regulations for disposal classification.
UN Number: 1993
UN Proper Shipping Name: Flammable Liquid, N.O.S. (contains 1,2-Bis(trimethoxysilyl)ethane)
Transport Hazard Class: 3
Packing Group: III
Environmental Hazards: Not classified as marine pollutant
Special Precautions for Transport: Secure containers upright. Protect from heat, moisture, and rough handling during transit. Ensure labeling and placards meet current transport regulations.
Safety, Health, and Environmental Regulations/Legislation Specific for the Substance: Listed in TSCA Inventory (US), REACH (EU), AICS (Australia), DSL (Canada). Subject to use restrictions and personal protective requirements in workplace settings.
OSHA Status: Considered hazardous by definition of Hazard Communication Standard.
SARA Title III: Not listed as an extremely hazardous substance, but may be subject to reporting if large amounts are stored.
California Proposition 65: Contains chemicals known to the State of California to cause reproductive toxicity (methanol is a potential hydrolysis byproduct).
WHMIS (Canada): Classified as a hazardous product.
Other International Regulations: Complies with GHS labeling, registration, and safety requirements in major jurisdictions.
