Product Name: 3-Acetoxypropyltrimethoxysilane
Chemical Formula: C8H18O5Si
CAS Number: 53988-87-7
Recommended Use: Used as a coupling agent, crosslinking agent in adhesives, coatings, and sealants for plastics, glass, and metal surfaces
Manufacturer: Information available on the label or bill of lading
Emergency Phone: Contact available through local poison control or emergency services
Email Contact: Safety compliance team at supplier company
Classification: Flammable liquid; Eye irritation; Skin irritation; Harmful if inhaled
Label Elements: Flammable, harmful health symbol, exclamation mark for skin and eye irritation
Hazard Statements: Causes severe eye damage, skin irritation, inhalation may result in respiratory tract irritation, vapors can form explosive mixtures with air
Precautionary Statements: Keep away from heat and open flame, avoid breathing vapors, wear protective gloves and enclosed goggles, use in well-ventilated area
Health Effects: Short-term exposure may cause dizziness, headache, and central nervous system depression; prolonged contact can result in dermatitis
Substance: 3-Acetoxypropyltrimethoxysilane
Chemical Identity: 3-(Trimethoxysilyl)propyl acetate
CAS Number: 53988-87-7
Concentration: 98-100% by weight
Impurities: Trace methanol, acetic acid (potentially under 0.5%) due to hydrolysis
Stabilizing Additives: None declared by most manufacturers
General Advice: Move patient to fresh air immediately upon exposure, remove contaminated clothing
Eye Contact: Rinse thoroughly under running water for at least 20 minutes, seek medical attention
Skin Contact: Wash affected area thoroughly with soap and water, seek medical treatment if irritation persists
Inhalation: Remove to fresh air, rest, and consult physician if symptoms persist
Ingestion: Rinse mouth, do not induce vomiting unless instructed by medical personnel, get medical help
Most Important Symptoms: Burning sensations in nose or throat, eye pain, redness, blistering skin, difficulty breathing after inhalation
Flammability: Flammable liquid, emits toxic fumes under fire conditions
Suitable Extinguishing Media: CO2 foam, dry chemical, alcohol-resistant foam
Unsuitable Media: Direct water stream can splash product, increasing risk of spreading
Special Hazards: Methanol and acetic acid vapors may form under heat, risk of explosion with air
Personal Protective Equipment: Self-contained breathing apparatus, fire-resistant clothing
Advice for Firefighters: Cool fire-exposed containers with water spray, avoid run-off entering drains
Personal Precautions: Evacuate area, ventilate thoroughly, prevent skin and eye contact with spillage
Protective Equipment: Impermeable gloves, safety hood or full face shield, chemical-resistant boots
Environmental Precautions: Prevent liquid from entering drains, sewers, waterways
Cleanup Methods: Absorb with inert material such as dry sand, collect in chemical waste container
Decontamination: Wash spill site with plenty of water, monitor area for vapor residue
Handling: Use non-sparking tools, only handle with good ventilation, keep container tightly closed
Precautions: No eating, drinking, or smoking during use, avoid contact with skin, eyes, or clothing
Storage Conditions: Store in original, sealed containers in cool, dry, well-ventilated area away from heat or ignition
Incompatible Materials: Water, moisture, strong oxidizers, acids and bases accelerate decomposition
Maximum Storage Temperature: Below 30°C is recommended to maintain stability
Occupational Exposure Limits: No established limit for this compound, monitor for methanol (< 200 ppm TWA ACGIH)
Ventilation: Local exhaust or explosion-proof general ventilation, especially in confined spaces
Protective Gloves: Butyl rubber or nitrile gloves provide effective barrier
Eye Protection: Chemical safety splash goggles with face shield
Respiratory Protection: Organic vapor respirator if vapors exceed exposure limits
Other Protection: Chemical-resistant apron, long-sleeved garments to prevent skin exposure
Appearance: Colorless to pale yellow transparent liquid
Odor: Faint acetic ester odor
Odor Threshold: Not established
pH: Can hydrolyze to acetic acid, expect slight acidity upon exposure to moisture
Melting Point: Below -50°C
Boiling Point: Between 225°C
Flash Point: Between 85°C (closed cup)
Evaporation Rate: Moderate (<1, n-butyl acetate=1)
Flammability: Flammable liquid
Vapor Pressure: 1.2 mmHg at 25°C
Vapor Density: About 5 (air=1)
Relative Density: 1.04 g/cm³
Solubility: Reacts with water, soluble in organic solvents
Partition Coefficient: Log Kow not established for parent compound; hydrolysis products likely more hydrophilic
Auto-ignition Temperature: Data not available
Decomposition Temperature: Above 250°C
Viscosity: 2.5 mPa.s at 25°C
Stability: Stable under recommended storage and handling; reacts with moisture
Chemical Reactivity: Undergoes hydrolysis in presence of water, forming methanol and acetic acid
Hazardous Reactions: Exothermic reaction with water, may release flammable vapors
Conditions to Avoid: Moisture, elevated temperatures, open flames
Incompatible Materials: Acids, bases, oxidizers, water
Decomposition Products: Methanol, acetic acid, carbon monoxide, silicon oxides under fire conditions
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Moderate; LC50 (rat, inhalation) estimated > 10 mg/L/4h; oral LD50 (rat) 1800 mg/kg
Skin Irritation: Causes moderate to severe irritation after prolonged or repeated contact
Eye Irritation: Causes severe irritation, possible corneal injury
Sensitization: No known sensitization from reported industry handling
Chronic Effects: Data gap; repeated exposure to hydrolysis byproducts (methanol, acetic acid) can damage nervous system, liver
Carcinogenicity: Not classified based on available data; methanol and acetic acid not confirmed carcinogens at expected exposure levels
Mutagenicity: No evidence provided in current literature
Ecotoxicity: No quantified aquatic toxicity values, but hydrolysis can release methanol and acetic acid, which are toxic to aquatic life
Persistence and Degradability: Breakdown to methanol and silicic acid in presence of water; methanol degrades rapidly in environment
Bioaccumulative Potential: Low for parent compound and metabolites
Mobility in Soil: Likely to leach due to water solubility of hydrolysis products
Other Adverse Effects: Large spills or routine discharges may lower pH in aquatic systems, harm vegetation and soil invertebrates
Waste Treatment Methods: Incinerate in approved facility or treat as hazardous chemical waste
Contaminated Packaging: Rinse thoroughly, dispose in accordance with federal and local regulations
Environmental Hazards: Avoid discharge to waterways, ground, and drains
Handling Precautions: Work with certified waste disposal contractor familiar with organosilanes and hydrolysis byproducts
Special Instructions: Do not reuse empty containers, ensure cleanliness before recycling or discarding
UN Number: UN1993
Proper Shipping Name: Flammable Liquid, N.O.S. (3-Acetoxypropyltrimethoxysilane mixture), if shipped above threshold quantity
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Labels Required: Flammable liquid, keep containers upright and secure
Special Precautions for User: Check container integrity before and after shipping, placard vehicle accordingly, transport according to local/national regulations
Environmental Hazards: None specified, avoid transportation with incompatible materials
TSCA: Listed in United States Toxic Substances Control Act Inventory
REACH: Registered or preregistered by European manufacturers/importers
OSHA: Regulated as hazardous chemical, requires workplace controls
SARA: Subject to Section 313 reporting depending on usage and threshold
Other Regulations: Subject to Workplace Hazardous Materials Information System (WHMIS) in Canada; hazard communication required under GHS standards
Labeling Requirements: Product label should carry GHS/CLP signal words, pictograms, and hazard statements
