Product Name: 3-Aminopropylmethyldiethoxysilane
Chemical Family: Organosilane
CAS Number: 3179-76-8
Alternative Names: 3-(Diethoxymethylsilyl)-1-propanamine, Silane, 3-(aminopropyl)methyldiethoxy-
Recommended Use: Industrial manufacturing, coatings, adhesives, sealants, primers
Supplier: Contact manufacturer or distributor for details
Emergency Contact: Reference local poison control or chemical emergency service
GHS Classification: Flammable liquid (Category 3), Acute toxicity – oral (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A), Sensitization – skin (Category 1)
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, harmful if swallowed, causes skin irritation, causes serious eye irritation, may cause skin sensitization
Pictograms: Exclamation mark, flame
Precautionary Statements: Keep away from ignition sources, avoid breathing vapors, wash skin thoroughly after handling, use only outdoors or in well-ventilated area, wear protective gloves/eye protection/face protection, in case of accident: call poison center
Chemical: 3-Aminopropylmethyldiethoxysilane
CAS Number: 3179-76-8
Concentration: ≥98%
Impurities: Trace alkoxysilanes, ethanol (from hydrolysis), other proprietary trace levels not contributing to overall reactivity or toxicity
Inhalation: Move person to fresh air, provide oxygen if breathing is difficult, seek medical attention if symptoms like coughing or dizziness occur
Skin Contact: Remove contaminated clothing, rinse skin with copious amounts of water, wash with soap, seek attention if irritation persists
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical advice
Ingestion: Rinse mouth, do not induce vomiting, call poison center or physician, give nothing by mouth to an unconscious person
General Advice: Show this safety data sheet to the doctor or first responders
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide, water spray
Specific Hazards: Vapor forms explosive mixtures in air, combustion produces toxic gases including nitrogen oxides, silicon oxides, carbon monoxide
Protective Equipment: Wear self-contained breathing apparatus, full protective gear
Firefighting Instructions: Cool containers exposed to fire, prevent runoff from entering drains, use water spray to keep containers cool, avoid inhalation of combustion products
Personal Precautions: Evacuate area, remove ignition sources, use protective equipment, prevent breathing in vapors
Environmental Precautions: Prevent release to sewers, water bodies, or soil
Cleanup Methods: Absorb with inert material (sand, earth, vermiculite), collect in suitable containers for disposal, clean spill area with water and detergent, ventilate area
Disposal: Handle as hazardous waste, follow local regulations for disposal
Handling: Use only in well-ventilated areas, avoid contact with skin, eyes, and clothing, keep away from heat, sparks, open flames, do not breathe vapor, avoid ingestion
Storage Conditions: Store in tightly closed, original containers, keep in cool, dry, well-ventilated location, keep away from incompatible materials (water, strong oxidizers), protect from moisture and air
Storage Incompatibility: Avoid strong acids, alkalis, oxidizing agents, water
Specific Recommendations: Label all storage containers clearly, implement secondary containment for bulk storage
Exposure Limits: No established OSHA or ACGIH limits, monitor workplace exposure where possible
Engineering Controls: Use local exhaust ventilation, maintain eyewash and safety shower stations nearby
Personal Protection: Wear chemical-resistant gloves (e.g., nitrile), safety goggles, impervious clothing, face shield where splashing possible
Respiratory Protection: Use NIOSH-approved respirator in areas of poor ventilation or high vapor, use in accordance with 29 CFR 1910.134
Hygiene Measures: Wash thoroughly after handling, remove contaminated clothing immediately, do not eat, drink, or smoke while handling
Appearance: Clear, colorless to pale yellow liquid
Odor: Slight amine odor
pH: Not applicable (hydrolyzes in water)
Melting Point/Freezing Point: < -70°C
Boiling Point/Range: Approx. 225°C
Flash Point: 90°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid and vapor
Explosion Limits: Not available
Vapor Pressure: 0.23 hPa @ 20°C
Vapor Density (air=1): >1
Density: 0.91 g/cm³ @ 25°C
Solubility: Reacts slowly with water, soluble in alcohol and most organic solvents
Viscosity: 1.42 mPa.s @ 25°C
Partition Coefficient (n-octanol/water): Not determined
Decomposition Temperature: Not established
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: May react with water, acids, oxidizing agents
Hazardous Reactions: Contact with water generates ethanol and silanols, which further polymerize
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, silicon dioxide, formaldehyde in high heat
Conditions to Avoid: Heat, sparks, open flames, exposure to moisture
Incompatible Materials: Water, oxidizers, strong acids, bases
Acute Toxicity: Oral LD50 (rat): approx. 2995 mg/kg, Dermal LD50 (rabbit): >2000 mg/kg
Skin Corrosion/Irritation: Causes moderate skin irritation
Serious Eye Damage/Irritation: Causes serious eye irritation
Respiratory or Skin Sensitization: May cause allergic skin reaction, possible respiratory irritation
Chronic Effects: Prolonged exposure can cause central nervous system effects, liver damage in rare cases
Carcinogenicity: Not classified as carcinogen by IARC, NTP, or OSHA
Mutagenicity: Not expected to be mutagenic based on available data
Reproductive Toxicity: No data suggesting developmental or reproductive toxicity in humans
Other Effects: Inhalation of vapors can produce nausea, headache, drowsiness at high concentrations
Ecotoxicity: Harmful to aquatic life, LC50 (fish, 96h): >100 mg/L, EC50 (Daphnia, 48h): >100 mg/L
Persistence and Degradability: Hydrolyzes slowly in water to form silanols and ethanol, breakdown products degrade in soil and water
Bioaccumulative Potential: Low potential due to hydrolysis and low log Kow
Mobility in Soil: Moderate, will hydrolyze and bind to soil minerals over time
Other Adverse Effects: No evidence of significant ozone depletion, photochemical reactivity, or microtoxicity
Waste Treatment Methods: Incinerate in approved facility, do not pour down drains or sewers
Contaminated Packaging: Dispose containers as hazardous waste, make sure containers are empty before disposal
Other Considerations: Follow local, regional, and national regulations for chemical waste; consult regulatory authorities for proper classification
UN Number: UN 1993
UN Proper Shipping Name: Flammable liquid, n.o.s. (contains 3-Aminopropylmethyldiethoxysilane)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Environmental Hazards: Not classified as marine pollutant
Special Precautions: Ensure proper placarding, carry emergency response guide, avoid rough handling
Regulations: Ship according to DOT, IMDG, IATA requirements
TSCA Status: Listed
REACH Status: Registered, subject to restrictions in EU
OSHA Hazard Communication: Meets criteria for hazardous chemicals
SARA Title III: Not subject to Section 302/304; minimal Section 313 reporting if in large scale
California Proposition 65: Not listed
Other National Inventories: Listed on DSL (Canada), AICS (Australia), ENCS (Japan)
Labeling Requirements: Comply with GHS labeling and worker education on chemical hazards
