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3-Isocyanate Propyl Methyl Dimethoxy Silane: A Modern Chemical Shaping Performance and Safety

Historical Development

Commercial chemistry saw a jump in the 1950s when organosilanes emerged for electronics, coatings, and adhesives. Over decades, research dialed into unique silanes equipped to bridge organic and inorganic worlds. 3-Isocyanate Propyl Methyl Dimethoxy Silane, sometimes called IPMS, grew from that trend. Developers hunted for ways to make surfaces last longer, bond tougher, and resist the elements. The isocyanate group and the silane backbone build a chemical that grabs hold of unreactive surfaces—glass, metal, ceramics—then offers that same durability inside advanced polymers and coatings. Firms in the late 20th century noticed their lab trials cut production headaches and trimmed maintenance costs downstream. The hunger for high-performance, weather-resistant, and chemically stable compounds across Europe, America, and Asia helped 3-IPMS grow from a lab curiosity into a specialty chemical seen in demanding sectors.

Product Overview

3-Isocyanate Propyl Methyl Dimethoxy Silane carries the versatility that modern manufacturing craves. This molecule brings together a methyl group, two methoxy groups, a propyl bridge, and an isocyanate “hook”—allowing it to latch onto a huge range of surfaces. Used as a crosslinking agent, primer, adhesion promoter, and functional modifier, IPMS finds its way into paints, adhesives, sealants, electronic encapsulants, and surface modification treatments. Its structure lets it take part in chemical reactions where both organic and inorganic partners need convincing to work together. That opens doors for everything from long-lasting architectural coatings to automotive parts designed for years of vibration and exposure.

Physical & Chemical Properties

In the lab, this silane usually appears as a clear to pale yellow liquid. It carries a sharp odor, warning handlers of its high reactivity, especially thanks to the isocyanate group. Density floats around 1.05 g/cm³ at room temperature, showing little fluctuation during standard storage. Boiling point rides close to 210°C. It resists water for a short stretch but hydrolyzes quickly without careful handling, splitting off methanol in the process. This feature matters during storage and application, since unwanted water vapor can start a chain reaction, creating foam or causing uneven reactions in production systems. Its chemical stability under dry air lets suppliers promise a reasonable shelf life, but moisture control is the golden rule.

Technical Specifications & Labeling

Producers assign batch purity using gas chromatography, aiming for levels above 98% for industrial users. Regulatory agencies, especially in Europe, demand exact isocyanate content and residual solvents for safety. Manufacturers must label containers with hazard symbols tied to respiratory sensitization, skin irritation, and other risks linked to isocyanates. Transport packaging needs to be leak-proof and protected from rain, marked with UN numbers, proper shipping names, and safety instructions covering accidental exposure or environmental spills. Technical data sheets list boiling range, flash point, water sensitivity, and key compatibility guidelines, offering users no-nonsense checklists for inventory and workplace safety audits.

Preparation Method

Most producers build IPMS through a reaction between 3-aminopropyl methyl dimethoxy silane and phosgene or alternatives such as triphosgene for smaller productions. The aminopropyl silane reacts under dry, inert conditions with phosgene, churning out hydrochloric acid as a byproduct. That acid needs strict neutralization before any downstream use, prompting investment in rinsing and purification equipment. Larger facilities recapture solvents and byproducts to cut environmental impact and trim production costs. From personal experience working with polyurethane intermediates, the challenge usually involves balancing safety—especially with hazardous intermediates like phosgene—and yield, since customers want high-quality silanes without leftover amine or excess isocyanate. Proper process engineering, fume extraction, and automated controls play a big role in preventing accidents.

Chemical Reactions & Modifications

The isocyanate functionality on IPMS makes it an eager participant in polymer chemistry. It reacts with alcohols, amines, and water in situ, leading to urethane, urea, or carbamate linkages. This characteristic sets the stage for cross-linking networks in resins and adhesives. The silane side of the molecule undergoes hydrolysis, generating silanols and eventually siloxane bonds with mineral or glass surfaces. Surface engineers in the aerospace and construction sectors benefit from this dual chemistry, achieving stronger adhesion between epoxy layers and reinforcing fibers or metallic substrates. Modification strategies explore swapping methoxy groups for ethoxy versions to tweak hydrolysis rates or incorporating longer propyl chains for added flexibility and compatibility in resins.

Synonyms & Product Names

Industry shorthand lists this specialty silane as IPMS, but catalogs mention names like 3-Isocyanatopropylmethyldimethoxysilane and Silane, 3-isocyanato-propylmethyldimethoxy-. Some suppliers use trade names tied to their product lines, offering unique blends targeted for adhesives, sealants, or electronic encapsulants. Sometimes confusion happens, as a few names overlap with similar silanes, so reference to CAS numbers offers the only solid guarantee of getting the right chemical. In procurement, accuracy with these identifiers prevents costly errors during raw material substitutions, especially for formulators juggling multiple silanes in their recipes.

Safety & Operational Standards

Workshops and warehouses following best practices keep their silane storage cool, dry, and well-ventilated. Handling calls for more than just gloves—operators wear chemically resistant full-sleeve clothing, splash goggles, and in many facilities, air-purifying respirators. Anyone in the coating or plastics business learns fast that isocyanates spark allergies and asthma in unprotected workers, making local exhaust and airtight process lines the standard, not the luxury. Management often runs air-monitoring programs and demands medical surveillance for workers exposed even briefly to these chemicals. Fire risk rises around open flames or sparks, thanks to flammable solvent residues, so all containers need grounding and strict housekeeping to avoid accidents. Emergency kits on site feature absorbents and neutralizers, allowing for quick response in case of a spill, while regular drills embed safety habits across the team.

Application Area

3-Isocyanate Propyl Methyl Dimethoxy Silane makes its biggest impact in industries chasing ultimate durability from coatings and adhesives. Glass companies rely on it to anchor polymer layers to panes, boosting shatter resistance on windshields and architectural glass panels. Electronics makers turn to IPMS for potting and encapsulation, using its cross-linking ability to seal circuit boards and protect sensitive parts from corrosive atmospheres. Paint labs develop weatherproof, abrasion-resistant coatings for bridges, skyscrapers, and marine vessels, counting on the silane to bridge metals, concrete, and polymers. Tire and automotive plants use it in reinforcing fillers, aiming for stronger bonds and longer tread lifespans. Even solar panel manufacturers experiment with it as a primer for tough, UV-exposed environments. My conversations with coating formulators and safety engineers point to a consensus: companies keep coming back to this chemistry when they want something that stands up to heat, moisture, and heavy use.

Research & Development

Labs devoted to adhesives, composites, and protective coatings keep pushing the envelope with IPMS. Recent years brought advances in coupling efficiency, reducing processing times and improving wetting on new high-tech glass surfaces. Development teams test new polymer matrices designed to interact more precisely with the isocyanate or silane sides, fine-tuning peel strength and resistance to water or solvents. Data from collaborative studies between academic and industrial partners gives formulation specialists real numbers on how molecular tweaks change bulk performance. A noticeable drive exists toward greener synthesis, driven by stricter regulatory frameworks on isocyanate emissions and end-of-life recycling. Some groups focus on replacing the more hazardous reagents, adopting continuous flow reactors and alternative phosgenation chemistries. The future direction looks strong, with biotechnology innovations entering trials to monitor and even self-repair silane-modified surfaces.

Toxicity Research

Toxicologists flagged isocyanates decades ago for their potential to harm lungs and skin. 3-Isocyanate Propyl Methyl Dimethoxy Silane falls under close observation, since inhaling or skin contact can set off rashes, asthma, and chronic sensitization. Researchers in Europe and the US tackled chronic exposure by measuring airborne levels during material application and evaluating the breakdown products released during use and thermal degradation. Safety studies showed that short, sharp exposures could set off lifelong allergies, shaping training and shift patterns for workers. Animal studies painted a picture of moderate acute toxicity, driving medical managers to demand quick decontamination protocols and first-responder training on site. Ongoing projects in government and industry strive to pin down the safe thresholds and suggest alternatives to lower exposure and process risk even further, especially as engineered nanomaterials begin mixing into silane-enhanced products.

Future Prospects

Growing demands for reliability in civil infrastructure and electronics keep driving investments in chemicals like IPMS. Green chemistry is stepping into the spotlight, with companies experimenting to cut emissions both upstream and downstream. As stricter rules roll out worldwide on volatile organic compounds and workplace hazards, the next surge in innovation will likely spring from safer reagent systems and automated, closed-process lines. On the research side, universities and startups grow their focus on long-term stability studies, especially for renewable energy systems, 5G infrastructure, and electric vehicles loaded with sensitive semiconductors. The grown-up value of this chemistry isn’t just about function—it’s about balancing performance and human health, making tough choices guided by both regulatory standards and lessons learned from field experience and ongoing lab investigations.




What is 3-Isocyanate Propyl Methyl Dimethoxy Silane used for?

Why Chemists and Manufacturers Turn to This Compound

Walk through any modern factory in the coatings or adhesives industry, and you’re bound to bump into this tongue-twister of a chemical: 3-isocyanate propyl methyl dimethoxy silane. Beneath the long name sits a molecule that packs power in crosslinking. This just means it helps different materials connect better, stick together more tightly, and last longer when exposed to the elements. Think of sticking a heavy mirror to a tiled wall: no one wants that coming down. Here, the silane takes charge, helping the adhesive stay tough even in damp bathrooms or busy kitchens.

What This Chemical Means for Everyday Products

People might glaze over when hearing about silanes, but their work shows up in daily life. That protective finish that keeps a stone countertop from soaking up red wine—there’s a good chance silane treated the surface. Rain bouncing off a high-rise window owes part of its water resistance to this molecule. In the world of paints and coatings, it helps designers give us walls that don’t peel or bubble after a long, humid summer. The silane’s isocyanate group teams up with a resin or hardener to create bonds tough enough to fight heat or heavy cleaning chemicals.

Longevity and Safety: More Than Buzzwords

Lasting strength matters. Workers rely on adhesives treated with this compound for building bridges, trains, and wind turbines. Fewer cracks or separations mean fewer repairs and safer outcomes. As someone who’s dealt with water-damaged walls in old houses, the benefits hit close to home. Products that shrug off water, dirt, or sunlight take the sting out of costly fixes down the line. In automotive shops, windshield sealants get a silane boost to stand up to rain, cold, and highway speeds.

Every chemical brings tradeoffs. 3-isocyanate propyl methyl dimethoxy silane must be handled with care, especially before curing, because isocyanate groups can cause breathing irritation or allergic reactions. Good ventilation and protective gear matter at job sites. Manufacturers screen for safer ways to use and package this material, but responsibility sticks with both makers and end-users. Europe’s REACH rules ask for detail on handling and safe use, so workplaces keep training up-to-date.

What Sets This Compound Apart

Without the silane family, modern construction and electronics would feel stuck in the past. This specific molecule doesn't just do one thing; it helps build bridges—literally and figuratively—between materials that usually reject each other. Folks can bond plastics to glass or metals and expect performance over years, not months. Whether it’s the strength of a medical adhesive or the flexibility of a new sealant on drought-stricken farmland, the silane provides a silent backbone.

Looking Beyond Today: Seeking Improvement

Sustainability raises questions. Chemical makers keep working on methods that lower emissions during silane production. Researchers look for ways to replace traditional solvents with greener choices that cut pollution and energy waste. Any step that lifts performance without raising health risks gets attention. As climate and safety demands grow, industry needs to balance chemical might with responsibility. Tougher standards for exposure, smarter training for workers, and clearer labels help everyone use these tools more carefully.

There’s no need to be a chemist to appreciate how much easier silane compounds have made life. From my own experience with repairs and renovations, choosing products with a backbone like this one means less hassle and a better finish that lasts. As industries keep raising the bar, finding smarter, safer ways to harness this chemical’s power matters not only for business but for families, towns, and the future of construction.

What are the handling and storage requirements for 3-Isocyanate Propyl Methyl Dimethoxy Silane?

Getting Real About Hazards

Working with 3-Isocyanate Propyl Methyl Dimethoxy Silane puts safety right in your face. This chemical’s isocyanate group—responsible for its reactivity—can cause nasty reactions with water or even regular old air humidity, creating toxic gases. I remember visiting a plant where a small spill led to major problems because a vent fan failed. The chemical hit wet surfaces and released vapor that sent three workers to the hospital. All of that started with a storage mistake.

Storage: Keep It Cool, Keep It Dry, Keep It Sealed

Manufacturers and handlers often treat storage as an afterthought. I’ve seen drums set next to exterior warehouse walls, exposed to sunlight, and allowed to sweat. Heat kicks off decomposition or reactions, while moisture guarantees hydrolysis. The result? Not only product loss but also exposure to fumes that can burn lungs and eyes.

The right move: Keep this chemical in a temperature-controlled spot, below 25°C if possible. Avoid the classic rookie mistake of storing it near wash stations, open doors, or pipes dripping condensation. Dry interior shelving, with spacing to avoid accidental knocks, reduces heartbreak. Tightly sealed, corrosion-resistant containers block air and moisture. I lean toward thick HDPE drums, but stainless steel with airtight gaskets works too. Never use containers made of materials that degrade or react with isocyanates.

Handling: PPE Is Not Optional

You can tell who’s serious about health by how they suit up. Anyone transferring or working with this substance needs more than a pair of gloves. Isocyanates hit skin fast. The wrong gloves—think latex—melt or don’t block skin exposure. Go for butyl rubber or heavy nitrile. Full-face respirators defend against vapors. Don’t rely on open windows for ventilation; local exhaust systems with filters keep air clear. I’ve seen many skip these steps, and the result is always doctors, not higher productivity.

Parents Don’t Let Kids Play in Chemical Storage

Even experienced workers cut corners sometimes. Training should never end up as a ten-minute slideshow. Everyone—from new hires to chemical engineers—should walk through a real spill drill yearly. I found practical training works best, muscle memory taking over in a crisis.

Eye on Regulations, Not Just Labels

OSHA and REACH lay out plenty of rules, but people slack off, thinking labels are enough. Take each requirement seriously, not just because the law says so, but because the chemical doesn’t care how long you’ve been on the job. Regular audits help; one surprise check at a former client’s plant caught five expired respirators and a leaking cap. Action came right after, not six months later.

Solutions: Make Mistakes Harder to Happen

Automation works well for limiting human error. Closed-system pumps and dedicated transfer lines cut the need for workers to lug open containers. Alarms for temperature or humidity changes give an early warning before problems spiral.

Reinforcing a culture where safety beats speed is simple but often ignored. I’ve found that giving people a real voice in safety improvements gets more buy-in than fancy posters or slogans. Listen to the folks on the floor. They often know the weak points in any storage or handling system.

Handling 3-Isocyanate Propyl Methyl Dimethoxy Silane with respect keeps people healthy and businesses running. In my experience, shortcuts here cost real dollars—and sometimes far more—down the line.

Is 3-Isocyanate Propyl Methyl Dimethoxy Silane hazardous to health?

Understanding the Substance

Anyone who works around industrial chemicals hears a lot about hazard labels, gloves, and fume hoods. 3-Isocyanate Propyl Methyl Dimethoxy Silane isn’t a household name, but its use in adhesives, coatings, and sealants means people can come into contact with it during manufacturing or construction. Inhaling, touching, or even getting droplets in the eyes could present a risk, something safety sheets and regulations don’t take lightly.

Assessing Health Risks

Silane-based chemicals like this one matter because they combine two notorious groups: isocyanates and silanes. Anyone who’s developed a cough or skin rash after using industrial adhesives knows the trouble isocyanates bring. Occupational Safety and Health Administration (OSHA) and Environmental Protection Agency (EPA) put strict exposure limits on isocyanates for good reason. Reports connect them to asthma, skin irritation, and eye problems in workers who never wore full protection. For sensitized people, even tiny amounts in the air can cause lung trouble that won’t fade after a quick cleanup.

Methyl dimethoxy silane brings its own bag of tricks: it reacts with moisture to give off methanol during curing. Methanol can hurt eyesight, damage nerves, or cause headaches and nausea if the airborne levels in a workspace climb. Combining these risks, someone using 3-Isocyanate Propyl Methyl Dimethoxy Silane without good ventilation or sturdy gloves just takes a gamble with their health. My own days handling chemical sealants taught me the smell and tickle in the nose aren’t the worst; it’s what follows days or weeks later—a rash that just won't ease up, or a cough that comes back every time you touch the material again.

Regulation and Real-World Exposure

Regulatory agencies inspect workplaces and review chemicals based on case studies, accident reports, and lab tests. The European Chemicals Agency (ECHA) points to the need for proper labeling and personal protective equipment (PPE) whenever this silane gets used in manufacturing. In the US, companies pay hefty fines if workers fall sick due to poor training on handling these substances. People who deal directly with the chemical face danger if their training gets skipped or PPE supplies run short. The risk goes up in hot workplaces with little airflow, where volatile compounds can linger in the air.

Health trackers point to construction and automotive lines as particular hotspots. Here, repeated exposure has led to more reported cases of allergic reactions, eye injuries, and even chronic respiratory problems. I’ve seen co-workers avoid reporting symptoms out of worry for job security, even as the wheezing got worse. Management must take responsibility to provide safety data sheets in plain language and rotate team members, so no one takes the brunt of repeated exposure.

Paths Forward: Reducing Harm

Solutions stand out once you look past the jargon. Companies should keep chemical inventories updated, substitute less risky chemicals where possible, and run ventilation fans every time material gets mixed or poured. Training—hands-on, not just a quick video—helps workers spot early warning signs of overexposure. Regular health checks and honest discussions about symptoms should replace a “tough-it-out” culture.

Sourcing and using chemical-resistant gloves, proper respirators, and sealed eyewear makes a difference. Seeing real, long-term health damage in peers drives home the message: PPE isn’t just a formality. Legislation only helps if the workplace treats every safety step as more than an afterthought.

Final Thoughts

3-Isocyanate Propyl Methyl Dimethoxy Silane offers industrial benefits, but health costs pile up fast when safety practices slip. My experience shows risk isn’t theoretical—the wrong move has a face, a name, and a medical bill. Managing these hazards starts with respect for both the science and the real lives on the line.

What is the shelf life of 3-Isocyanate Propyl Methyl Dimethoxy Silane?

Chemical Storage Isn’t a Guessing Game

Anyone who’s ever handled specialty chemicals gets the same headache: How long can this bottle sit on the shelf before it turns into an expensive risk? 3-Isocyanate Propyl Methyl Dimethoxy Silane stands out for its efficiency in surface modification, bonding, and advanced material applications, but people rarely talk about what happens after it’s been opened and left in storage. Shelf life, here, becomes more than a manufacturing detail—it determines whether labs stay productive and safe or deal with lost batches and recalls.

Why Shelf Life Shouldn’t Go Unchecked

From direct experience, I’ve seen labs miss production deadlines just because someone assumed that silane derivatives age like wine. This just doesn’t happen. Most suppliers stamp the shelf life at about 12 months if the container stays sealed and dry, away from moisture. Even inside a climate-controlled storage room, ambient humidity sneaks in every time the lid comes off, nibbling at product quality. Moisture triggers hydrolysis for these isocyanate-based silanes. By the time product residue thickens or the smell gets sharp, it could already be too late for a quality result.

Facts, Not Fears: What Science Tells Us

Peer-reviewed research and technical sheets highlight the same basic risk: hydrolytic instability. The functional group in 3-Isocyanate Propyl Methyl Dimethoxy Silane reacts with water. Leaving it in a humid room, even for just a day, takes months off its useful life. A published test from a specialty chemicals supplier found product degradation in as little as three months when stored with subpar sealing. Hydrolysis breaks key bonds, introduces unwanted by-products, and kills reactivity. Deteriorated silane doesn’t just slow processing down—it can compromise adhesion, reduce surface coverage, and weaken the final material, setting off a cascade of failures in paint, plastics, and electronics.

Quality Assurance on the Front Lines

From jobs in R&D and manufacturing, I’ve learned that success depends on discipline. Tech experts recommend frequent checks. Open the drum, pull a small sample, and run a simple FTIR or NMR scan. Any sign of increased viscosity or a shift in the spectrum tells the operator it’s time to replace stock. Sometimes it feels unnecessary to test before every use, but one bad batch does far more damage than a half-hour spent checking a sample.

It’s About Culture, Not Just Chemistry

Labs with tight inventory controls and regular audits never scramble to replace spoiled silane before a shift deadline. Investing in good desiccators and airtight lids pays long-term dividends. People need to see proper sealing, handling, and record-keeping as cost-saving moves, not chores. Teams who ignore shelf life, hoping short-term luck will cut corners for them, carry consequences down the production line. Missed shelf life shortens product lifespan, wastes expensive raw materials, and risks worker safety with chemical by-products nobody wants to inhale.

Better Practices, Better Products

Reliable suppliers don’t just print expiry dates—they document packaging quality and offer guidance on storage. When a shipment comes in, log a clear receipt date. Use color tags or software alerts to track opening and closing dates. Hold quick trainings on product handling, not just for managers but also for each shift worker. Each of these habits means fewer spoiled batches and bigger returns on investment. Treating chemicals like 3-Isocyanate Propyl Methyl Dimethoxy Silane as delicate, not disposable, boosts results everywhere from research labs to high-volume factories.

How should 3-Isocyanate Propyl Methyl Dimethoxy Silane be disposed of?

A Chemical with Bite

Walk into any lab or industrial paint shop, and sooner or later, you’ll hear the name 3-Isocyanate Propyl Methyl Dimethoxy Silane tossed around. It’s used in coatings, adhesives, and sometimes for giving glass or metal surfaces an edge in bonding. People often overlook what should happen once a canister runs empty or leftovers linger in the storage room. I have watched more than a few nervous glances pass between technicians when the subject of disposal comes up. Let’s face it, no one wants to end up on the wrong side of an emergency response phone call.

Hazards Hide in Plain Sight

I remember, during an early career stint, a contractor dumped a half-used bottle straight into a mop sink. The stench that hit the room brought everyone running. This stuff isn’t harmless. Its isocyanate group can irritate skin and lungs—the dust or vapor especially. Don’t even think about just mixing it with regular trash or washing it down the drain. Local bodies like the EPA list this silane among the hazardous chemical crowd for good reasons, linking improper handling to air and water pollution.

Rules Don’t Make Suggestions

Federal and state regulations won’t take kindly to shortcuts. Chemists and shop workers should know the playbook: check the Safety Data Sheet (SDS) and call in the hazardous waste team, not the janitor. My own habit is to put every container marked with a hazard label—especially anything containing residual isocyanate—directly in the dedicated hazardous waste bin after using up as much as possible for its task. That only works because our facility partners with a certified disposal contractor. Trying to fudge these steps or use a general landfill never ends well. I’ve heard from peers who’ve paid stiff penalties for less.

Practical Steps That Work

Start by collecting all waste, including contaminated gloves and rags, in tightly sealed containers that resist chemical attack. Use containers marked for hazardous organics or isocyanates, skip the temptation to reuse soda bottles or random metal cans. I remember scraping together funding for proper disposal drums during a lean project stretch. Even when no one’s watching, it pays off in the long run—health issues or environmental cleanup costs dwarf the up-front expense.

After gathering waste, alert the designated hazardous waste handler. In many regions, licensed firms come and handle both the pickup and transportation. Some company safety officers arrange quarterly pickups to stay compliant and prevent stockpiling. Avoid open-air storage or mixing with other chemicals that might kick up dangerous reactions—water especially, since silanes react and can release toxic vapors, making room evacuations real events.

Solutions Beyond Just Following Rules

Training is a quiet hero here. I push new staff through chemical waste handling workshops. The difference shows: mistakes drop, confidence rises, and no one fumbles with panic when something splashes. Community awareness matters too. Local governments sometimes run hazardous waste drop-off days. For smaller labs or art studios, these programs mean people don’t have to chance risky disposal on their own.

We live with synthetic chemicals for all the right reasons—stronger composites, more lasting finishes—but keeping the leftovers from harming workers or sneaking into groundwater can’t be left to chance. It just takes a bit of discipline, sturdy containers, and the kind of training that doesn’t wear thin under pressure.

3-Isocyanate Propyl Methyl Dimethoxy Silane
Names
Preferred IUPAC name 3-isocyanatopropyl(trimethoxy)methylsilane
Other names 3-Isocyanatopropyltrimethoxysilane
3-Isocyanatopropyl(dimethoxy)methylsilane
γ-Isocyanatopropylmethyl-dimethoxysilane
NCO silane
Silane, isocyanatopropyl methyl dimethoxy
Pronunciation /ˈθriː aɪˌsəʊ.si.əˌneɪt ˈprəʊpɪl ˈmiːθəl ˌdaɪməˈθɒksi ˈsaɪleɪn/
Identifiers
CAS Number 15396-00-6
3D model (JSmol) `3Dmol Ta0vcJMLZKZP4kmBSSnAh7dNOpd`
Beilstein Reference 1465587
ChEBI CHEBI:189559
ChEMBL CHEMBL2110959
ChemSpider 3335806
DrugBank DB14624
ECHA InfoCard 03b11e10-86b2-4aa7-b609-cd9667a0ecfc
EC Number 82985-35-1
Gmelin Reference 1262118
KEGG C19455
MeSH Cyanates
PubChem CID 11450104
RTECS number VR3325000
UNII 2VZ1WS0932
UN number 3334
CompTox Dashboard (EPA) DTXSID3047353
Properties
Chemical formula C7H15NO3Si
Molar mass 237.32 g/mol
Appearance Colorless transparent liquid
Odor Sharp, musty
Density 1.010 g/cm3
Solubility in water Reacts with water
log P 1.6
Vapor pressure 0.2 hPa (20°C)
Basicity (pKb) pKb ≈ 3.5
Refractive index (nD) 1.4170
Viscosity 10 mPa·s
Dipole moment 2.99 D
Thermochemistry
Std molar entropy (S⦵298) 459.5 J·mol⁻¹·K⁻¹
Pharmacology
ATC code V04CX
Hazards
Main hazards Harmful if swallowed, causes skin irritation, causes serious eye irritation, may cause respiratory irritation.
GHS labelling GHS02, GHS05, GHS07, GHS08
Pictograms GHS02,GHS05,GHS07
Signal word Warning
Hazard statements H317, H318, H334, H335
Precautionary statements P261, P264, P271, P272, P280, P285, P302+P352, P304+P340, P305+P351+P338, P310, P312, P337+P313, P342+P311, P362+P364, P403+P233, P501
NFPA 704 (fire diamond) 2-3-1
Flash point > 53°C
Autoignition temperature 230 °C
Lethal dose or concentration LD50 (Oral, Rat): > 2000 mg/kg
LD50 (median dose) LD50 (median dose): Oral rat LD50 > 2000 mg/kg
NIOSH GVK93670G5
PEL (Permissible) Not established
REL (Recommended) 0.021 mg/m³
Related compounds
Related compounds 3-Isocyanatopropyltriethoxysilane
3-Isocyanatopropyltrimethoxysilane
3-Isocyanatopropylmethyldiethoxysilane
3-Isocyanatopropylmethyltriethoxysilane
3-Aminopropylmethyldimethoxysilane