Chemical Name: N-Octyltrichlorosilane
Synonyms: Octyltrichlorosilane, Trichloro(octyl)silane
CAS Number: 5289-45-0
Manufacturer/Supplier: Industry laboratory suppliers, chemical manufacturers
Recommended Uses: Silanization agent, surface treatment, chemical intermediate
Contact Information: Manufacturer's address, emergency contact phone
Restrictions: Use in well-ventilated labs, avoid household uses
GHS Classification: Skin Corrosion/Irritation Category 1B, Serious Eye Damage Category 1, Acute Toxicity (inhalation, dermal, oral) Category 3, Specific Target Organ Toxicity (single exposure) Category 3
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage, harmful if inhaled or in contact with skin. Releases toxic fumes on contact with water. Irritates mucous membranes, eyes, skin, respiratory tract.
Pictograms: Corrosive, Exclamation Mark, Health Hazard
Precautionary Statements: Avoid breathing vapors or dust. Wash thoroughly after handling. Wear protective gloves, clothing, eye and face protection. Seek immediate medical advice for exposure.
Chemical Identity: N-Octyltrichlorosilane
Concentration: >95% active ingredient
Impurities or Stabilizing Additives: Trace hydrochloric acid generated by hydrolysis, possible solvent residue (toluene, hexane, <2%)
Molecular Formula: C8H17Cl3Si
EC Number: 226-548-9
Inhalation: Move person to fresh air quickly. Keep at rest in a position comfortable for breathing. Seek medical attention promptly if symptoms of respiratory irritation or distress arise.
Skin Contact: Remove contaminated clothing. Rinse skin thoroughly with running water for at least 15 minutes. Call a poison center or doctor. Burns require immediate medical care.
Eye Contact: Rinse cautiously with water for at least 15 minutes, lifting upper and lower eyelids. Remove contact lenses if present and easy to do. Get emergency ophthalmological treatment.
Ingestion: Do not induce vomiting. Give water to rinse mouth if victim is conscious. Immediate transport to hospital is essential.
Urgent Symptoms: Breathing difficulty, blisters, corrosive burns, persistent coughing, severe eye pain
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, foam approved for chemical fires
Unsuitable Media: Water spray or foam will react with chemical; avoid direct water streams
Hazardous Combustion Products: Hydrogen chloride, silicon oxides, toxic fumes including carbon monoxide and dioxide, phosgene possible
Special Protective Equipment: Full-face self-contained breathing apparatus, chemical protective clothing
Unique Hazards: Containers may explode in fire. Vapors may form explosive mixtures in air. Use extinguishing agents from safe distance.
Additional Instructions: Cool adjacent containers with fog, avoid runoff into waterways
Personal Precautions: Evacuate unnecessary personnel. Wear full-body protection including chemical-resistant gloves, goggles, and a respirator. Ventilate enclosed areas.
Environmental Precautions: Prevent dispersion into soil, drains, surface waters. Stop leak if possible without risk. Notify authorities if contamination occurs.
Methods for Clean-up: Absorb spillage with inert materials like vermiculite or dry sand. Scoop residues into sealable containers. Neutralize with dilute sodium hydroxide before disposal. Clean area with plenty of water while using a fume hood or local exhaust.
Further Advice: Avoid contact with water in large volumes; hydrolysis creates corrosive hydrochloric acid.
Safe Handling: Avoid inhalation, ingestion, and contact with skin or eyes. Only handle in properly ventilated spaces such as a functioning fume hood. Open containers slowly to control vapors.
Storage Requirements: Store in tightly sealed containers made of compatible material and kept in a cool, dry location away from direct sunlight. Keep apart from moisture, acids, and oxidizing substances.
Conditions to Avoid: Humidity, open flames, sources of ignition, incompatible chemicals including alcohols and alkalis. Do not store above room temperature.
Packing Materials: Use original, approved containers made of glass or high-density polyethylene. Ensure labels are intact.
Incompatibility: Reacts dangerously with water, strong bases, oxidizers, alcohols, amines
Occupational Exposure Limits: No NIOSH or OSHA PEL assigned; treat as highly hazardous. Workplace monitoring recommended.
Engineering Controls: Chemical fume hood essential. Local exhaust ventilation and eyewash/safety shower nearby.
Protective Equipment: Nitrile gloves, lab coat, chemical splash goggles, face shield. Use a NIOSH-approved respirator for vapor/mist exposure risk.
Hygiene Measures: Wash hands after handling. Do not smoke, eat, or drink near work area. Remove contaminated clothing before leaving laboratory.
Environmental Exposure Controls: Keep material away from storm drains, surface water, and soil. Install spill containment where possible.
Appearance: Colorless to pale yellow liquid
Odor: Sharp, acrid, similar to hydrochloric acid
Odor Threshold: Not established
pH: Decomposes in water
Melting Point/Freezing Point: Not available; liquid at room temperature
Boiling Point/Range: 110–113°C at 13 mmHg
Flash Point: 100°C (closed cup)
Evaporation Rate: Not determined
Flammability (solid, gas): Not flammable as sold, vapors may ignite
Vapor Pressure: ~1 mmHg at 25°C
Vapor Density: heavier than air
Relative Density: 1.02 g/cm³ at 25°C
Solubility: Decomposes in water, soluble in organic solvents (toluene, hexane)
Partition Coefficient (log Kow): Not determined
Auto-ignition Temperature: Not determined
Decomposition Temperature: Evolves hydrochloric acid on hydrolysis
Viscosity: Not measured
Chemical Stability: Stable under dry, inert conditions
Reactivity: Hydrolyzes rapidly upon contact with moisture, releasing corrosive hydrochloric acid fumes. Reacts exothermically with bases, water, and alcohols.
Hazardous Reactions: Dangerous exothermic reaction on contact with water, strong oxidizing agents, strong alkalis
Conditions to Avoid: Heat, humid air, open flames, incompatible substances
Hazardous Decomposition Products: Hydrogen chloride, silicon dioxide, small amounts of carbon oxides
Polymerization: Not expected under normal conditions
Acute Toxicity: Oral, inhalation, and dermal exposure cause severe damage. Inhalation LC50 (rat, 4hr): data not specified, but causes respiratory distress, pulmonary edema risk. Corrosive to eyes, skin, mucous membranes.
Chronic Effects: Prolonged or repeated exposure may lead to dermatitis, chronic respiratory irritation.
Skin Irritation: Rapidly causes chemical burns, blistering
Eye Damage: Causes irreversible tissue destruction, risk of blindness
Sensitization: Data not detailed, but similar silanes exhibit low allergenicity
Carcinogenicity/Mutagenicity: Not considered a carcinogen or mutagen under current regulatory frameworks
Target Organs: Lungs, mucous membranes, skin, eyes
Additional Notes: Immediate medical treatment is vital for serious exposure scenarios
Aquatic Toxicity: Hydrolysis products cause significant harm to aquatic organisms by acidifying water. Expected low persistence in water due to rapid breakdown.
Persistence and Degradability: Hydrolyzes within minutes to hydrochloric acid and octylsilanetriol, both of which dilute and disperse rapidly.
Bioaccumulation Potential: No significant bioaccumulation anticipated for hydrolysis products.
Soil Mobility: Moderate mobility in soil after hydrolysis, may alter pH, affecting microflora.
Other Harmful Effects: Large-scale spills threaten aquatic life, soil bacteria, and local water quality. Ecosystem recovery depends on neutralization and dispersion.
Waste Treatment Methods: Chemical incineration under controlled conditions, or neutralize carefully with dilute sodium hydroxide before disposal of liquid or rinse water.
Container Disposal: Triple-rinse containers with suitable solvent, then incinerate or arrange for hazardous waste collection.
Disposal Restrictions: Do not release to environment or general sewer systems.
Regulatory Requirements: Follow local, regional, and national disposal regulations for hazardous chemicals. Contact licensed disposal contractor
Waste Code: Consult facility and jurisdictional hazardous waste codes for halogenated organic residues
UN Number: UN 2987
UN Proper Shipping Name: Alkyltrichlorosilanes, n.o.s. (N-Octyltrichlorosilane)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II
Labels Required: Corrosive, Marine Pollutant if applicable
Special Precautions: Keep drums upright, secured, away from food, acids, moisture.
Other: Emergency Response Guidebook (ERG) code: Consult relevant edition for spill, fire protocols in transit.
Global Inventories: Listed on US TSCA, EU REACH, Canada DSL/NDSL, Japan ENCS
OSHA: Treated as hazardous by definition; hazard communication program necessary
SARA Title III: Not subject to Section 302; subject to Sections 311/312 category (acute hazard)
EPA: Regulated toxic substance, release reporting may apply
REACH Information: Registered substance, Safety Data Sheet required for supply within Europe
State Regulations: Check California Proposition 65, New Jersey, Massachusetts right-to-know laws
Other Regulatory Notes: Proper labeling and employee safety training required for users, strict adherence to storage and transport rules enforced by multiple agencies.
